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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
A higher dose of a medication may be required to see an effect.higher dose of a medication may require an enlargement of the blood vessels, which may increase the risk of side effects.
  • Cialis (tadalafil) can interact with certain foods and beverages, which may increase the level of tadalafil in your blood by blocking its absorption in the gastrointestinal tract. This can amplify blood pressure-lowering effects to dangerous levels. Avoid consuming grapefruit or grapefruit juice while taking Tadalafil.
  • Cialis (tadalafil) can interact with certain foods and beverages, which may increase the level of tadalafil in your blood by blocking its metabolism by enzymes called PDE5. This can amplify blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Tadalafil.
  • Tadalafil (sildenafil) is a phosphodiesterase-5 (PDE-5) inhibitor, which is used to treat erectile dysfunction by enhancing blood flow to the penis.
  • Cialis

    Cialis (tadalafil) is a medication used to treat erectile dysfunction (ED) and symptoms of benign prostatic hypertrophy (enlarged prostate). It is sometimes prescribed as a generic medicine. ED is a common condition in men and is often treated with medications.

    Cialis is also sometimes prescribed to men who do not get and take nitrates (medicines used to treat angina).

    If you take tadalafil to treat erectile dysfunction or benign prostatic hyperplasia (enlarged prostate), it relaxes the muscles in the prostate and bladder, allowing blood to flow into the penis. The medication then begins to accumulate in the urethra and arteries. Tadalafil can cause side effects such as pain, nausea, and dizziness. If you experience an erection that lasts longer than 4 hours or if it is painful, stop taking tadalafil and seek medical help right away.

    Tadalafil is also sometimes prescribed to men who have (hypertension), an enlarged prostate, or heart problems. The medication works by relaxing blood vessels, increasing blood flow, and causing symptoms of high blood pressure.

    Tadalafil can also be used to treat (low testosterone).

    Uses of Cialis

    Cialis is used to treat erectile dysfunction and benign prostatic hyperplasia in men. It is also sometimes used to treat symptoms of benign prostatic hypertrophy (enlarged prostate). The medication relaxes the muscles in the prostate and bladder, increasing blood flow, and causing symptoms of enlarged prostate.

    Treatment for ED

    Tadalafil is sometimes used to treat ED in men who are not able to get or maintain an erection. ED is a common condition that affects more than 1 in 4 men globally. It can also be treated with medicines (ED medications) that are also used to treat other conditions including:

    • Blood flow problems
    • Low testosterone
    • Heart problems
    • BPH symptoms

    How to use Cialis

    The recommended dosage of Cialis for men is one tablet taken about one hour before sexual activity. You should take it about 60 minutes before you plan to have sex. Cialis may be taken with or without food. Cialis should not be taken more than once a day.

    Side Effects of Cialis

    Like all medications, Cialis can cause side effects. Most side effects are mild and go away as your body adjusts to the medication. Common side effects include:

    • Headache
    • Blurred vision
    • Dizziness
    • Muscle pain
    • Nausea
    • Oidepressant-like symptoms

    Less common side effects can include:

    • Back pain
    • Burning or flushing
    • Diarrhea
    • Flushing
    • Nasal congestion

    More serious side effects can include:

    • Allergic reactions (rash, itching, swelling)
    • Stomach pain
    • Blood disorders
    • Liver problems

    • Allergic reactions (swelling)
    • Blood disorders (high levels of potassium, magnesium, or bile acid)

    If you experience any of these serious side effects, stop taking Cialis and seek medical help right away.

    Although most of these side effects are mild, they can happen. If you experience any of these common side effects, stop taking Cialis and contact your doctor right away.

    It is not advisable to drink alcohol while taking Cialis or for more than a few hours after taking it because it can cause severe side effects like dizziness, fainting, and changes in vision. It is also not recommended for use in children and adolescents under 18 years of age.

    Read moreCialis (tadalafil) for Men FDA-Approved DrugTadalafil for Men Generic Drug Approval DrugUS FDA Not for Use in U.

    Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

    You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

    There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

    • Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

    • Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

    for chest pain or use Rectogesic ointment?

    • Nicorandil (Ikorel), used to treat angina

    • Cimetidine, used to treat stomach or duodenal (peptic) ulcers

    • Theophylline, used to treat asthma

    • Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

    • Anti-fungals such as itraconazole and ketoconazole

    • Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

    • Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

    • Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

    • Recreational drugs:- amyl nitrate (poppers)

    If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

    Read available consultation questionnaire

    What is Tadalafil?

    Tadalafil is the generic version of the drugs

    which are commonly prescribed to treat erectile dysfunction.

    Tadalafil is a phosphodiesterase (PDE) inhibitor medicine used to treat erectile dysfunction by men with erectile dysfunction when a man has problems with sexual performance or ability to get an erection.

    Tadalafil: How it worksHow Tadalafil works

    Tadalafil’s active ingredient is Tadalafil.

    It works by opening up the blood vessels that supply the penis during sexual stimulation to allow the blood vessels that supply the penis to relax and expand.

    This can make it easier to get an erection and it will also allow for better sexual performance.

    Tadalafil is more than the body can absorb and about the same number per milliliter as (Cardura, Allopurin etc).

    It can increase the blood pressure levels but also have it called maximum recommended daily dose (MMDD) or maximum quantity of daily drug.

    Tadalafil affects the way other PDE5 inhibitors work, as well as any other, which is why it is important to take it at the the same time as your other medications will depend on the content of your other medications to be taken including prescription (Cardura, Allopurin etc). There are certain groups of people who would benefit from taking Tadalafil alongside any other Tadalafil than the body would be at increased risk of side effects.

    You can try following these tips and simple fact from describing how the medicine works for you.

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    Tadalafil is a prescription drug

    Read the fact and orderabout Tadalafil.

    We take your time and understand your unique situation;

    • If you are from your heart condition and have it temporarily problems your heart, make sure to discuss your medical history with your GP before you are taken alongside Tadalafil.

    Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

    You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

    There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

    • Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

    • Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

    for chest pain or use Rectogesic ointment?

    • Nicorandil (Ikorel), used to treat angina

    • Cimetidine, used to treat stomach or duodenal (peptic) ulcers

    • Theophylline, used to treat asthma

    • Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

    • Anti-fungals such as itraconazole and ketoconazole

    • Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

    • Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

    • Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

    • Recreational drugs:- amyl nitrate (poppers)

    If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

    Read available consultation questionnaire information online

    Do not take Tadalafil if you have ever had an allergic reaction to any of the following ingredients. Any of the ingredients mentioned in the questionnaires consultation questionnaire. The list of ingredients can be found at the.

    There are no controlled clinical studies in any known forms to suggest the safe use of Tadalafil for Vitis-yne. Nealous abnormalities have been reported in some patients taking Tadalafil and have been associated with an increased risk of. Of particular concern were the examinations of the scalp and/or the anterior pelvic pain/fainting after taking Tadalafil (caused by a painful erection) or having it taken for any length of time (caused by a prolonged erection). These patients have a very low risk of this problem and are generally very unlikely to have an. However, there are a few cases where a Vitis-yne has taken Tadalafil and has developed. These cases have been reported solely on the symptoms which are the subject of the questionnaire. These cases have been published in a medical journal and have found no evidence of a link between taking Tadalafil and an increased risk of. However, in these cases, it is not known whether the Vitis-yne may have taken Tadalafil.